The problem, three ways
Curious
Imagine a universe that is finite and has no edge. If every loop you could draw in it can be shrunk to a point, must it be, as far as its shape goes, a sphere? Henri Poincaré asked in 1904. Grigori Perelman proved the answer is yes in 2002 and 2003.
Undergraduate
A closed 3-manifold with trivial fundamental group is homeomorphic to S³. The analogues in higher dimensions were proved first: by Smale for dimension five and above, and by Freedman for dimension four. Perelman completed Hamilton's Ricci flow programme, which deforms a metric towards roundness and cuts out the singularities that form.
Specialist
Perelman's entropy functionals, non-collapsing and canonical neighbourhood theorems control Ricci flow with surgery, yielding Thurston's geometrisation conjecture, of which Poincaré is a corollary. Detailed expositions by Kleiner and Lott, Morgan and Tian, and Cao and Zhu appeared in 2006.